Your genome.Decoded.
An open source AI agent harness that turns your AI agent into a personal DNA expert. Runs on your machine.
Introducing Genomi.
What if my ClineGooseCursorGemini CLIOpenClawHermes AgentCodexClaude Code can help answer which evidence is strong enough to trustmy 1000 Genomes reference-neighbor contextwhether I carry a BRCA variantwhether I can digest milkwhether my DNA changes drug responsehow much Alzheimer's risk I inheritedwhether I carry cystic fibrosiswhat this rsID meanshow I metabolize warfarinwhy coffee keeps me up ?
The way your genome should work.
Interactive
Static reports → live conversation.
Local-first
Your raw DNA stays on your machine.
Evidence-aware
Each answer carries source limits.
Open & Compatible
Plugs into any AI agent. One install.
From genome to insights. Four steps.
Install
Have your agent follow INSTALL_FOR_AGENTS.md.
Point at your raw genome data
Read from disk. Nothing is uploaded.
Build the Active Genome Index
A local SQLite index for focused evidence tools.
Interact with it
Ask questions, cross-check evidence, or render a dashboard.
Your Personal DNA Expert.
Active Genome Index
Your genome source becomes a local, queryable SQLite index.
Libraries
ClinVar, HPO, GenCC, references, PharmCAT, ancestry, and more.
Journal
Append-only investigation notes and reviewed source findings.
Skills and MCP
Host skills route to validated tools and capability dispatch.
Your genome, answered.
Pharmacogenomics
PharmCAT, ClinPGx, FDA-label, and PGxDB context.
Nutrigenomics
Curated single-marker nutrient and tolerance evidence.
Polygenic Risk
PGS Catalog search, import, overlap, and score calculation.
Monogenic Conditions & Carrier Status
ClinVar exact matching plus HPO and GenCC disease evidence.
Sequence & Regions
Translation, ORFs, primers, restriction sites, and region features.
Ancestry & Population Genetics
1000 Genomes PCA projection and reference-neighbor context.
Your raw genome,
never uploaded.
Genomi keeps raw genome sources, parsed indexes, and reference libraries on local disk. Host agents may send selected evidence snippets to the model they use; choose a local model or zero-retention API when that policy matters.