Setup

Get from zero to your first genome report in five steps. Total time: about ten minutes, plus however long your testing company takes to email the raw data download.

1. Paste this into your AI agent

Open your AI agent of choice (Claude, ChatGPT, Gemini, or any other agent that can read and write local files) and paste the prompt below into a new conversation.

Paste this into your agent, retrieve and follow https://raw.githubusercontent.com/genesresearch/genomi/main/install.md

This is the same one-liner from the homepage COPY button. The agent fetches install.md, which tells it what Genomi is, how to install it, and how to drive it.

2. Create a new folder for your personal genome expert

This folder will be your agent's working directory. Your genome lives here, the report lives here, and everything Genomi generates lives here.

Open Terminal and run (swap the path for any location you prefer):

mkdir -p ~/Documents/genomi

On Windows (PowerShell):

mkdir "$HOME\Documents\genomi"

Just remember the path. You'll need it in the next step.

3. Move your raw DNA file into the folder and tell your AI agent its location

Move your raw DNA file (.txt, .csv, .vcf, .bam, or .fastq, gzipped is fine) into the folder you just made. From Terminal:

mv ~/Downloads/AncestryDNA.txt ~/Documents/genomi/genome.txt

On Windows (PowerShell):

mv "$HOME\Downloads\AncestryDNA.txt" "$HOME\Documents\genomi\genome.txt"

Swap AncestryDNA.txt for whatever your provider gave you. Renaming it to genome.txt is optional, but it makes the next step easier. You can also drag the file in Finder or File Explorer if you prefer.

Then tell the agent where it is:

My raw DNA file is at ~/Documents/genomi/genome.txt.

Don't have a raw DNA file yet?

You can download yours from whoever sequenced or genotyped you. Sign in to the account you used to order the test, then follow the steps for your provider below.

If your file is zipped, leave it zipped. Genomi handles the common compressed formats.

4. Ask the agent to start processing using Genomi

Tell the agent something like:

Process my DNA with Genomi.

The agent will install Genomi if it isn't already on your machine, point it at your file, and run the analysis locally. Nothing leaves your computer.

5. Open the report, and keep talking

When Genomi finishes, it drops a dynamic HTML report in your folder and tells the agent where it is. Open it in your browser and start exploring.

From here you can:

• Keep chatting with the agent. Ask follow-up questions like "What does my APOE genotype mean?" or "Compare my caffeine metabolism markers to average." The agent has full access to your genome and the report.
• Interact with the report directly. Click into any section to drill down. The report is live, not static.

That's the loop: ask, expand, repeat.